Scientific research into aspects of the ageing process


The association between metabolites and BMI is independent of fasting status

Although metabolites change after consumption of a meal, the association between metabolites and BMI is similar after a night of fasting and after a meal. Bianca Schutte investigated the Growing Old Together study and published her work in the scientific journal Scientific Reports.

December 15 2016 Author: Leiden LangLeven

Announcement PhD defence Erik van den Akker and Mini Symposium

The dept. of Molecular Epidemiology is proud to announce the thesis defence of Ir. Erik van den Akker, which will take place next Wednesday February 18th at 11.15 AM, in the Academic Building, Rapenburg 73, Leiden. The title of his thesis is "Computational Biology in Human Aging - An Omics Data Integration Approach".

After the thesis defence....

February 01 2015 Author: Eka Suchiman

Would you prefer living like a jackrabbit or like a turtle?

One of Joris Deelen's proposition has been published in the Leiden University Newsletter for alumni. The proposition originated from his thesis ‘Genetic and biomarker studies of human longevity’, which Joris defended successfully with cum laude.

July 18 2014 Author: Molepi - Molecular Epidemiology

Erik identified robust markers of human ageing

The expression in blood of a novel gene network containing the ASF1A histon chaperone gene is a robust signature of human ageing. This observation was made by a collaboration of scientists from the Leiden University Medical Center (LUMC) and the Delft University of Technology (TU), The Netherlands. The ASF1A gene network, discovered in the joint analysis of four blood transcriptome studies and confirmed in an independent study, is indicative of chronological age and survival into old age. The findings were published online last week in the scientific journal “Aging Cell”.

November 29 2013 Author: MolEpi - Molecular Epidemiology

Missed the "Eureka!" episode on tv?


eureka hoe word ik honderd






Molepi was on television in KRO's programme Eureka! The subject of the episode was "How do I become hundred?"

October 18 2013 Author: molecular epidemiology - molepi

Eline Slagboom on local radio

Last September 5, Professor Eline Slagboom was being interviewed by the local Leiden radio-broadcasting station "Radio Sleutelstad" in it's program Technolab Leiden.

September 11 2013 Author: Molepi - Molecular Epidemiology

Joris Deelen wrote Aging Cell's most cited paper 2011-2012

The paper by Joris deelen et al. Aging Cell 2011 (Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited) is the top cited paper in Aging Cell in the period 2011-2012.

August 02 2013 Author: MolEpi - Molecular Epidemiology

Joris Deelen goes to the Gordon Research Conference in Boston and will be giving a talk

Our PhD student Joris Deelen will talk at the Gordon Research Conference Seminar (Human Genetics & Genomics) in Boston next Saturday. The talk is entitled: Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

Have a look at this link for the full programm of the Gordon Research Conference Seminar.

The Gordon Research Conference Seminar (July 6-7) will be held prior to the Gordon Research Conference (July 7-12, Bryant University Smithfield, RI)


July 02 2013 Author: Eka Suchiman

Eline Slagboom will give a talk at the 2nd International Conference on the “Genetics of Aging and Longevity”

Coming Monday April 23rd Eline will give a talk at the 2nd International Conference on the “Genetics of Aging and Longevity” in Moscow, Russia.

Her talk is entitled: "Genetic, epigenetic and genomic determinants of human longevity. "

April 20 2012 Author: Molepi - Molecular Epidemiology

Eline Slagboom is co-author in Nature Genetics paper

Osteoporosis is a common ailment among the elderly. It is often accompanied by bone fractures which are again bad for life expectancy. Half of people aged 80 and over break a hip die within one year.

It was known that there are hereditary factors in osteoporosis, but which were in the game was unclear so far. Now a publication in Nature Genetics shows that 56 areas on the DNA affect the risk of developing osteoporosis. Fourteen of them also affect the risk of bone fractures. Further research should reveal how the found genetic regions contribute to osteoporosis and whether medicine can intervene in the development of osteoporosis.

April 20 2012 Author: Molepi - Molecular Epidemiology


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