Scientific research into aspects of the ageing process


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Posted on 2015/07

Genetically determined prospect to become long-lived is associated with less abdominal fat and in particular less abdominal visceral fat in men

Sala,M.L., Roell,B., van der Bijl,N., van der Grond,J., de Craen,A.J., Slagboom,E.P., van der Geest,R., de Roos,A., Kroft,L.J.

Age Ageing 2015/07, Volume 44, Number 4, 713-717

Posted on 2015/05

Lifestyle and youthful looks

Gunn,D.A., Dick,J.L., van Heemst,D., Griffiths,C.E., Tomlin,C.C., Murray,P.G., Griffiths,T.W., Ogden,S., Mayes,A.E., Westendorp,R.G., Slagboom,P.E., de Craen,A.J.

Br.J.Dermatol. 2015/05, Volume 172, Number 5, 1338-1345

Posted on 2015/05

Visceral adipose tissue is associated with microstructural brain tissue damage

Widya,R.L., Kroft,L.J., Altmann-Schneider,I., van den Berg-Huysmans AA, van der Bijl,N., de Roos,A., Lamb,H.J., van Buchem,M.A., Slagboom,P.E., van Heemst,D., van der Grond,J.

Obesity.(Silver.Spring) 2015/05, Volume 23, Number 5, 1092-1096

Posted on 2015

An in vivo study on brain microstructure in biological and chronological ageing

Altmann-Schneider,I., de Craen,A.J., van den Berg-Huysmans AA, Slagboom,P., Westendorp,R.G., van Buchem,M.A., van der Grond,J.

PLoS.One. 2015, Volume 10, Number 3, e0120778

Posted on 2015

Associations between insulin action and integrity of brain microstructure differ with familial longevity and with age

Akintola,A.A., van den Berg,A., van Buchem,M.A., Jansen,S.W., Slagboom,E.P., Westendorp,R.G., van der Grond,J., van Heemst,D.

Front Aging Neurosci. 2015, Volume 7, Number , 92-

Posted on 2015

Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism

Jansen,S.W., Akintola,A.A., Roelfsema,F., van der Spoel,E., Cobbaert,C.M., Ballieux,B.E., Egri,P., Kvarta-Papp,Z., Gereben,B., Fekete,C., Slagboom,P.E., van der Grond,J., Demeneix,B.A., Pijl,H., Westendorp,R.G., van Heemst,D.

Sci.Rep. 2015, Volume 5, Number , 11525-

Posted on 2015

Insulin, aging, and the brain: mechanisms and implications

Akintola,A.A., van Heemst,D.

Front Endocrinol.(Lausanne) 2015, Volume 6, Number , 13-

Posted on 2014/08

Low computed tomography coronary artery calcium scores in familial longevity: the Leiden Longevity Study

Kroft,L.J., van der Bijl,N., van der Grond,J., Altmann-Schneider,I., Slagboom,P.E., Westendorp,R.G., de,Roos A., de Craen,A.J.

Age (Dordr.) 2014/08, Volume 36, Number 4, 9668-

Posted on 2014/06

MicroRNA-663 induction upon oxidative stress in cultured human fibroblasts depends on the chronological age of the donor

Waaijer,M.E., Wieser,M., Grillari-Voglauer,R., van Heemst,D., Grillari,J., Maier,A.B.

Biogerontology. 2014/06, Volume 15, Number 3, 269-278

Posted on 2014/06

Low mitochondrial DNA content associates with familial longevity: the Leiden Longevity Study

van Leeuwen,N., Beekman,M., Deelen,J., van den Akker,E.B., de Craen,A.J., Slagboom,P.E., 't Hart,L.M.

Age (Dordr.) 2014/06, Volume 36, Number 3, 9629-

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